Friday 12 November 2010

SEX, LIES, AND PHARMACEUTICALS

HOW DRUG COMPANIES PLAN TO PROFIT
FROM FEMALE FEAR OF SEXUAL DYSFUNCTION


By Ray Moynihan and Barbara Mintzes
COMMON GROUND MAGAZINE
October 2010, Issue 231
Special PHARMAFICTION issue

PRODUCING FEAR IN WOMEN ABOUT THEIR SEXUALITY

No booty-call partners on speed dial? 

Don’t beg for that hunka-hunka burnin’ love between laundry loads? 

Content to sigh dreamily at the Old Spice Guy ~
then doze off during the late-night news?

Ladies, what the heck is wrong with your sex drives?

Probably nothing, but international pharmaceutical companies are pushing a controversial new ailment ~ female sexual dysfunction ~ as a money-making marketing opportunity. To do this, they have to create scenarios that make potential "patients" believe they have something that requires repair.
At first I thought it was great but now I’m worried that…he might be getting reliant on it…and in some ways, you know, I don’t even like thinking about that, cause it’s like ‘God, does someone have to take a pill to have sex with me?’ ~ 33-year-old woman whose partner took Viagra.
During the last year or so, has there been a period of several months or more when you lacked interest in having sex? 

When you felt anxious about your sexual performance or were unable to achieve an orgasm? 

Was there an extended time when you had trouble getting aroused, experienced pain on intercourse or just didn’t find sex pleasurable?

If you answered ‘yes’ to just one of these survey questions, and you’re a woman, you could easily be classified as suffering from a brand new medical condition called ‘female sexual dysfunction’, or FSD.

First described in the textbooks only a few decades back, FSD is set to become the next blockbuster medical condition, coming soon to a doctor’s surgery near you. As the ups and downs of daily life are re-categorized as the symptoms of medical diseases, soon all of us will be sick.

One of the women who actually helped write the definitions of female sexual dysfunction puts it very clearly. ‘What once was considered normal,’ wrote American psychologist Sandra Leiblum, ‘has come to be considered dysfunctional.’


Nowadays, if a woman lacks the desire for sex, and is bothered by it, she could be diagnosed with a disorder of low libido. That’s just one of the four main disorders of female sexual dysfunction described in one of the leading manuals of diseases. The others include disorders of arousal, orgasm and pain. 

As the evidence plainly shows,
forces are fast amassing 
to tell you, and your doctor, 
that close to one in every two women 
suffers from some form 
of this new medical condition.

The giant pharmaceutical industry ~ with worldwide sales now approaching a trillion dollars a year ~ is hungrier than ever for new markets. In order to maximize sales, the industry must ‘create the need’ for its newest and most expensive products. Sometimes that means selling sickness to the wealthy healthy, helping transform common ailments into widespread conditions that require treatment with the latest pills. 

Applauded for producing medicines that extend life 
and ameliorate suffering, 
drug companies no longer simply sell drugs;
they increasingly sell the diseases that go with them.

Female sexual dysfunction is perhaps the perfect example of selling sickness, and the commercial firepower behind its forthcoming promotion is simply awe-inspiring.
‘With more than 50 million potential sufferers in the United States, FSD could offer a larger market than male sexual dysfunction,’ wrote a pair of enthusiastic market observers. 

‘FSD could be the next boon for pharma companies . . .’ 
If a drug is approved to treat this condition in the United States, the tsunami of marketing that will be unleashed in the media and on the web will soon swamp the shores of nations everywhere. 

According to industry reports, 
one company on the verge 
of having its product approved for women
had set aside 
$100 million for the drug’s advertising budget alone.

Three global corporations in particular have been at the forefront of the race to spread the word about this new medical condition and get their drugs approved to treat it. 
Pfizer, the biggest pharmaceutical company in the world and currently worth well in excess of $100 billion, has had high hopes that its wonder drug for men, Viagra, will also work for women. 

Procter and Gamble, with global annual sales of almost $80 billion, is famous for selling soap to housewives, but it also wanted to sell them testosterone patches as well. 

The third corporation featuring in this drama is the family-owned German outfit Boehringer, which boasts just over forty thousand employees and has affiliated companies in almost 50 countries. The German company’s pill targets the brain, with claims it can give women back their lost desire.
So what exactly is this condition called FSD? 

The answer depends a little on the solutions being sold at the time you ask the question. 
If Pfizer is promoting a drug that enhances blood flow to the genitals, then the condition might best be described as an ‘insufficiency’ of vaginal engorgement.
(However, Pfizer's research showed that genital blood flow increased in Viagra-treated women as they watched erotic videos, but the arousal did not make them desire sex.) 
 If Procter and Gamble is pushing its testosterone patch as a cure for women, the sexual disorder is discussed as a ‘deficiency’ of hormones. 

And if Boehringer has a pill that affects the mind’s neurotransmitters, women with low libido may have a ‘chemical imbalance’ in their brains. 

In a strange way, the disease seems designed to fit the drug. But there is also  a  deliberate attempt to portray common difficulties as if they’re symptoms of a medical disorder.

A forward-looking business intelligence report in 2003 named FSD drugs as an area of great future growth for the pharmaceutical industry, part of the burgeoning ‘lifestyle’ market including medicines for baldness, smoking cessation and obesity. 

The report was prepared for industry insiders and, with a hefty price tag, was never intended for public consumption. However, a leaked copy described how drug companies were ‘expanding the patient pool’ by using marketing campaigns to change public perceptions about things that used to be considered part of normal life. 

‘The medicalization of many natural processes,’ the report observed, ‘is creating markets for lifestyle drugs for those who want to optimize quality of life.’ It predicted that the market for FSD drugs could soon approach a billion dollars a year. 
.
By promoting the idea that ‘normal’ women
have explosive sex all the time,
BigPharma helped launch ‘female sexual dysfunction’

.
This is the ideal pleasure level my 68 year old Aunt Margie is supposed to desire reaching rather than be labeled dysfunctional? 

The days when the treatment of sex problems was dominated by the idea that therapy could render sexual inadequacy obsolete were quickly forgotten, swept away in a collective enthusiasm for new panaceas to treat this new dysfunction, and the billions that might flow from it. 
But the enthusiasm was not universal.

A New York university academic, Dr Leonore Tiefer, was by now pointing out in her writings that the post-sixties opportunities for the sexual emancipation of women were sadly being squandered in the medical takeover of sex.

Rather than attaining further freedom, the fear was that women were being subtly encouraged to feel inadequate, or even dysfunctional, if they failed to live up to a new unrealistic norm of a constant desire for sex. 
.

Right on cue, the new blue pill bounced straight from the doctor’s surgery to the centre of popular culture. 

Viagra famously made a cameo appearance in the television series Sex and the City when Samantha took the drug and apparently enhanced her already considerable sexual enthusiasm. Apart from her broader social critique, Tiefer was also busy documenting drug company sponsorship of all the important meetings where the new disorders were being developed. The resulting evidence offered a rare insight into the extraordinary extent of pharmaceutical involvement with an emerging field of medicine.

So very effective in the “treatment of erectile dysfunction in men,” Viagra has proven to be a “blockbuster” drug; a billion-dollar-generating marvel of a product! It worked. It changed lives. It was a ‘sexy drug’ in every sense of the term. It then became clear there was a great deal of money and power to be gained in the field of sexual dysfunction ~ money and power that could be exponentially multiplied if the market were expanded, which it would be if pharmaceutical 

MARKETING TO MEN AS A GLIMPSE
INTO THE FUTURE OF MARKETING TO WOMEN

When Viagra was first launched, older couples were used as models in advertising, and the United States ex-presidential candidate Bob Dole appeared in Pfizer’s commercials, speaking about his experiences using the drug after he’d had surgery for prostate cancer. Messages like this have rightly been credited with helping to de-stigmatize erection problems and allowing men to speak about what was a source of hidden personal shame. 

But as those who’ve tracked the advertising have observed, within a few short years the marketing strategy was shifting from a focus on older men and men with medical problems to a much broader and younger age group. In the United States, one of the few places in the world where it is legal to promote prescription pills direct to the public, there have been some classic advertisements helping to broaden the drug’s reach.

One magazine ad featured a close-up photo of a ruggedly handsome man around the age of 40 with the bold headline: ‘Viagra. It works for older guys. Younger guys. Even skeptical guys.’ Then, in the small print, the ad asked its readers: ‘Think you’re too young for Viagra? Do you figure, “It only happens once in a while so I’ll live with it”? Then nothing’s going to change, especially your sex life.’ The message was clear: even the most occasional erection problems could benefit from being treated with a drug. 

It wasn’t long, though, before the marketing seemed to be reaching out to an even wider group ~ men like the anonymous Canadian man interviewed elsewhere in this book who weren’t impotent at all, but simply wanted to enhance their sex lives. For North American readers, a lot of this advertising will be all too familiar, but for people living elsewhere the audacity of some of the claims will be simply fascinating..
.
Viagra television ads were ordered off the air yesterday  (2004) by the Federal Drug Administration, because they promised men better sex, but failed to give adequate warnings, including the dangers to men, usually older, who have cardiovascular disease
.
One high-profile television commercial featured a man and a woman walking down the street, shopping. They first look at high-heeled shoes and the man then admires a mannequin in sexy black underwear, as the voice-over says: ‘Remember that guy who used to be called “Wild Thing?” The guy who wanted to spend the entire honeymoon indoors? Remember the one who couldn’t resist a little mischief? Yeah, that guy.’ At this point, Viagra-blue horns sprout from behind the man’s head to a blast of trumpet. ‘He’s back,’ says the ad triumphantly, as the horns then become the V for Viagra.
 
And pretty soon Pfizer wasn’t the only company doing it, as the industry brought us Levitra and then later Cialis, with their rounds of promotion helping to further expand the market. 

Amid images of a woman’s flashbacks to romantic moments, a television commercial’s voice-over asked: ‘In the mood for something different? How about Levitra? Ask your doctor if Levitra is right for you. It’s the best way to experience that difference.’ The approach must have worked. For this class of medicines, the drug companies were soon spending far more on these advertisements than they were spending on sending sales representatives to visit doctors. Normally, it’s the other way round.

This focus on advertising to the public as a key promotional tool is very closely linked to how the condition of erectile dysfunction, or ED, has been expanded far beyond earlier definitions of male impotence. Inflated estimates of how many men suffer from the condition have subtly been mixed with suggestions that any degree of inability to have an erection, at any time, is too much. 

The implied message from so much of the advertising is that a younger man’s sexuality is the norm against which all men, at any age, should measure themselves. And that means the changes in sexuality that happen as we age can become portrayed as medical problems needing to be treated. 

That a man may have grown in experience and sensitivity as he’s aged, and may have become a better lover as a result, is simply not part of the picture. This construction of new norms is certainly something for which to watch out as the campaign to promote female sex drugs intensifies.



The silver bullet for women still remains elusive.
Diminished libido, now called hypoactive sexual desire disorder, is what most drugs have focused on. Effectiveness is judged by how many "satisfactory sexual events" the woman reports during the study period, typically three to six months. Unlike an erection, a satisfactory event is whatever the woman thinks it is, from cuddling to coitus. 

The Decreased Sexual Desire Screener, sponsored by Boehringer, is a simple, five-question survey that can be used by doctors who are not experts in the area to diagnose women with FSD instantly. One of the “yes” or “no” questions asks if her sexual desire has decreased in the past ~ and she simply ticks the correct box.

Perhaps she ticks off a box thinking of how she felt about sex right after the birth of a child, or when life itself had her stressed. Does this make her sexually dysfunctional?

The danger? Being prescribed a drug with potentially toxic side effects for no sound medical reason. Drug companies’ own research shows in measuring pleasurable sexual experiences, their own medicines had about the same small incremental shifts as placebos given to women.

"The drug companies are finding it very hard to find a drug that's safe and effective," author Ray Moynihan told CTV News."There's been a number of attempts over the last 10 years, and each of them has failed." 

Moynihan believes the claims of sexual dysfunction disorders in women are grossly exaggerated. He says that they are a marketing ploy by drug companies to find a pill that may not be the answer at all. 

"To try and reduce the complexity of what's going wrong for people sexually to the simplicity of a drug solution is absurd and it's part of the marketing," Moynihan said. 

Many sex therapists, like psychologist Dr. Lori Brotto, agree."It's certainly not a simple as, ‘Just give her a pill.'"

Interestingly, a whole new area of research is looking at the power of the placebo. Recent studies have found that just giving a woman a sugar pill she thinks will increase her desire can actually improve arousal. 
In study after study, placebos increased satisfying events almost or just as much as the actual drug. "There is something about the placebo response relating to the mind, and when you are anticipating, when you are expecting, it does translate into real change," Brotto said. 

That opens up a new avenue of treatment, without the side effects of medications, and confirms what many women have always suspected: the most powerful aphrodisiac is the right state of mind. No pharmaceutical fixes can hit the female erogenous zones, the brain and the funny bone.

Sometimes, all a woman needs is simply to know that she is wanted!

From the book Sex, Lies and Pharmaceuticals: How Drug Companies Plan to Profit from Female Sexual Dysfunction. © 2010, by Ray Moynihan and Barbara Mintzes. Published by Greystone Books, an imprint of D and M Publishers Inc.. Reprinted with permission of the publisher.

Ray Moynihan has been investigating the business of health care as a journalist for over a decade. He is the author and co-author of three previous books, including Selling Sickness, which has been translated into a dozen languages. He lives in Byron Bay, Australia.

Dr. Barbara Mintzes investigates the link between clinical trials and pharmacosurveillance evidence on drug safety and effectiveness. She is an assistant professor in the Department of Pharmacology and Therapeutics at the University of British Columbia.

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